SYNTHESIS OF SMALL MOLECULE HISTONE DEACETYLASE 6 DEGRADERS, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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专利权人:

Wisconsin Alumni Research Foundation

发明人:

Weiping Tang,Ka Yang,Hao Wu

申请号：

US16517943

公开号：

US20200022966A1

申请日:

2019.07.22

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Histone deacetylase (“HDAC”)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof； pharmaceutical compositions containing them； methods of using the composition to inhibit neoplastic cell growth in mammals, including humans.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/