Meizhong Xu;Colin Zhang;Yanlong Li;Brian W. Metcalf;Wenqing Yao;Jincong Zhuo
发明人:
Wenqing Yao,Meizhong Xu,Colin Zhang,Yanlong Li,Jincong Zhuo,Brian W. Metcalf
申请号:
US13279700
公开号:
US08288417B2
申请日:
2011.10.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.