A kind of novel molecular catalytic hydrolysis reaction is provided, and is different from zymoprotein. The catalytic hydrolysis reaction of the peptide of catalysis peptide of the invention is that at least one peptide (A1) selected from the group below arrives (A4) below. (A1) peptide includes battery timing group Tobin bronze/protein, box beam A and at least one upstream region and downstream area It include a part of region (A1) from wherein (A2) peptide (A3) peptide has hydrolysing activity and provides comprising amino acid sequence, passes through missing, substitution, addition and/or insertion one or (A1) or (A2) of multiple amino acid or amino acid sequence With the amino acid sequence (A1) or (A2) for attacking minimum 85% sequence homology with hydrolysing activity (A4) peptide and comprising amino acid sequence.