The invention relates to a method for removing a fluid medium (112) from a container (118). The method comprises the following steps: a) providing a removal device (116) having a closed inner chamber (122) that can be sterilized, wherein at least one needle element (138, 140) is received in the inner chamber (122), wherein the inner chamber (122) is closed by at least one sealing element (126) that can be perforated, b) providing the container (118) containing the fluid medium (112), wherein the container (118) comprises at least one container wall (162) having at least one segment (148) that can be perforated, c) connecting the removal device (116) and the container (118), wherein the segment (148) that can be perforated and the sealing element (126) that can be perforated are interconnected such that at least one protected area (166) is created between the segment (148) that can be perforated and the sealing element (126) that can be perforated, wherein the protected area (166) is closed by the connection at a substantially low germ count relative to an environment (170), and d) perforating the sealing element (126) that can be perforated and segment (148) that can be perforated by the needle element (138, 140), wherein the needle element (138, 140) penetrates the protected area (166).La invención se refiere a un método para remover un medio líquido (112) de un envase (118). El método comprende los siguientes pasos: a) proporcionar un dispositivo de remoción (116) que tiene una cámara interior cerrada (122) que puede esterilizarse, en donde se recibe al menos un elemento de aguja (138, 140) en el interior de la cámara (122), en donde la cámara (122) está cerrada por al menos un elemento de sellado (126) que puede perforarse, b) proveer el envase (118) que contiene el medio líquido (112), en donde el envase (118) comprende al menos una pared del envase (162) que tiene por lo menos un segmento (148) que puede perforarse, c) conectando el dispositivo de remoción (116
