A system for coordinating radiation therapy and imaging processes includes a radiation therapy system an radiation source mounted on a robotically-controlled system to move the radiation source about a subject to direct radiation to a target area in the subject according to a treatment plan. The system also includes an imaging system configured to acquire imaging data from a subject. The imaging system and the radiation therapy system are independently movable. The system also includes a coordination system configured to coordinate operation of the imaging system to acquire the imaging data from the subject during movement of the radiation source about the subject according to the treatment plan to avoid collisions of the radiation therapy system with the imaging system.
