O'DWYER, MICHAEL EAMON PETER,ODWYER, MICHAEL EAMON PETER
申请号：
CA2993796
公开号：
CA2993796A1
申请日:
2016.07.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
NK cells and NK cell lines are modified to increase cytotoxicity, wherein the cells and compositions thereof have a use in the treatment of cancer. Production of modified NK cells and NK cell lines is via genetic modification to remove checkpoint inhibitory receptor expression and/or add mutant (variant) TRAIL ligand expression.
