Sung Youb JUNG,Yong Ho HUH,Sung Hee PARK,Jong Soo LEE,In Young CHOI
申请号：
US14894222
公开号：
US20160129129A1
申请日:
2014.05.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a modified IgG4 Fc fragment useful as a drug carrier. When the modified IgG4 Fc fragment of the present invention is combined with an arbitrary drug, the resulting drug conjugate can minimize the effector functions of the IgG4 Fc and the chain exchange with in vivo IgG while maintaining in vivo activity and improving in vivo duration of the drug conjugate.
