JUNG, SUNG YOUB,HUH, YONG HO,PARK, SUNG HEE,LEE, JONG SOO,CHOI, IN YOUNG
申请号：
CA2913886
公开号：
CA2913886A1
申请日:
2014.05.29
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to a modified IgG4 Fc fragment useful as a drug carrier. The combination of an arbitrary drug and the modified IgG4 Fc fragment of the present invention minimizes the effector function by the IgG4 Fc, and the chain exchange with in vivo IgG, and can maintain the in vivo activity of a drug conjugate and improve the in vivo extended release thereof.
