ALBERS, RONALD J.,AYALA, LETICIA,CLAREEN, STEVEN S.,DELGADO MEDEROS, MARIA MERCEDES,HILGRAF, ROBERT,HEGDE, SAYEE G.,HUGHES, KEVIN,KOIS, ADAM,PLANTEVIN-KRENITSKY, VERONIQUE,MCCARRICK, MEG,NADOLNY, LISA
申请号:
CA2684999
公开号:
CA2684999C
申请日:
2007.04.25
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Provided herein are Aminopurine Compounds having the following structure (I), wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine. Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.