SIGNAL PHARMACEUTICALS, LLC;PHARMACOPEIA DRUG DISCOVERY, INC.
发明人:
ALBERS, RONALD,AYALA, LETICIA,CLAREEN, STEVEN S.,DELGADO MEDEROS, MARIA M.,HILGRAF, ROBERT,HEGDE, SAYEE,HUGHES, KEVIN,KOIS, ADAM,PLANTEVIN-KRENITSKY, VERONIQUE,MCCARRICK, MEG,NADOLNY, LISA,PALANKI, MO
申请号:
CA2595182
公开号:
CA2595182C
申请日:
2006.01.13
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Provided herein are Aminopurine Compounds having the following structure: (I)wherein R1 , R2 and and R3 are as defined herein, compositions comprising aneffective amount of an Aminopurine Compound and methods for treating orpreventing cancer, a cardiovascular disease, a renal disease, an autoimmunecondition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, anasbestos-related condition, pulmonary hypertension or a condition treatable orpreventable by inhibition of the JNK pathway comprising administering aneffective amount of an Aminopurine Compound to a patient in need thereof.