The invention pertains to a composition for the topical treatment of a keratosis, preferably a wart, comprising a halogenated acetic acid and an alpha-hydroxy acid. The invention further pertains to a dermal patch comprising this composition, and to kits comprising this composition and a patch, as well as to liquid plasters comprising the composition. Also, the invention pertains to the treatment of keratosis by contacting the keratosis with the composition.