AMINOAZOLE DERIVATIVE A compound, represented by the following formula or 5 a medically acceptable salt thereof, having an effect of regulating the activity of an androgen receptor. In the formula, X represents S, O； Z represents (R a)n-A-(CR 13 R14 )0- 1-(CR 11 R12 )0-1-； A represents aryl, heteroaryl； R 1 represents alkyl, cycloalkyl, alkenyl, alkynyl, 10 alkoxyalkyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl； R 2 represents hydrogen, halogen, alkyl, cycloalkyl, phenyl； R3 represents hydrogen, halogen, alkyl, cycloalkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkenyl, aryl, arylalkyl, heterocycle, heterocyclic alkyl, acyl, 15 cycloalkylcarbonyl, benzoyl, spiroalkyl, adamantyl, silyl, R 31 R32 NCO-； R 4 and R 5 represent hydrogen, halogen, alkyl, phenyl, and cycloalkyl. [Chem. 1] 20 [No Suitable Figure]
