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Indian alcohols substituted by [1.2.4] triazole [1.5-A] pyridine
- 专利权人:
- BRISTOL-MYERS SQUIBB COMPANY
- 发明人:
- RAMACHANDRA, ANUPAMA,HEDGE, SUBRAMAYA,SISTLA, RAMESH KUMAR,POSY, SHOSHANA L.,SHERWOOD, TREVOR C.,RATNA KUMAR, SREEKANTHA,PASUNOORI, LAXMAN,MUSSARI, CHRISTOPHER P.,MACOR, JOHN E.,LOMBARDO, LOUIS J.,HAQ
- 申请号：
- ARP170101788
- 公开号：
- AR108905A1
- 申请日:
- 2017.06.28
- 申请国别(地区):
- AR
- 年份:
- 2018
- 代理人:
- 摘要：
- Claim 1: a compound characterized by formula (1) or salt, wherein R1 is h, Cl, - CN, c83211；C83238331；-C (O) O (C₁₋₃ alkyl) or tetrahydropyranyl； each R² is independently halo, -CN, -OH, -NO₂⁺,C₁₋₃ alkyl, C₁₋₂ fluoroalkyl, C₁₋₂ cyanoalkyl, C₁₋₃ hydroxyalkyl, C₁₋₃ aminoalkyl, -O (CH₂) ₁₋₂OH, - (CH₂) ₀₋₄O (C₁₋₄ alkyl),C₁₋₃ fluoroalkoxy, - (CH₂) ₁₋₄O (C₁₋₃ alkyl),-O (CH) OC (O) (C alquilo)-O (CH) NR R-C (O) O (C₁₋₃ alkyl),-C (o) No. 696； (r696)；-696； - 696；-NRʸ (C₁₋₃ fluoroalkyl),-NRʸ (C₁₋₄ hydroxyalkyl),-739； (ch832222 (phenyl),-NRˣS (O) ₂ (C₃₋₆ cycloalkyl),-NRXC (O) (C₁₋₃ alkyl),-NRX (ch832222 cycloacrylonitrile)；C₃₋₆ cycloalkyl, morpholinyl, dioxothiomorpholinyl, methylpiperidinyl, methylpiperazinyl, amino-oxadiazolyl, imidazolyl, triazolyl or -C (O) (thiazolyl)；R³ is: (a) -L¹-A； or (b) H, C₁₋₆ alkyl, C₁₋₃ fluoroalkyl, C₁₋₃ cyanoalkyl, C₁₋₆ hydroxyalkyl, C₁₋₃ hydroxy-fluoroalkyl, -CRˣRˣCRˣ (OH) CRˣ = CRˣRˣ,-C 3DN (NR R)- (CRˣRˣ) ₁₋₄O (C₁₋₃ alkyl),- (CRˣRˣ) ₁₋₄O (CRˣRˣ) ₁₋₃O (C₁₋₃ alkyl),-CH₂CH (OH) CH₂O (C₁₋₃ alkyl),- (CR R) S (C alquilo)- (CH₂) ₁₋₃C₍O₎OC₍CH₃) ₃,- (CR R) NR R- (CR R) NR (C hidroxialquilo)-CH CH (OH) CH NR R-C (O) H -C (O) (C alquilo)-C (O) (C hidroxialquilo)-C (o) (c83231-833238 fluorine；-C (o) (c833217a) 833183323 chlorine tar；-C (O) (C cianoalquilo)- (CRˣRˣ) ₀₋₃C₍O₎OH, ₋C₍O₎₍CH₂) ₀₋₂O (C₁₋₄ alkyl),-C (O) (CR R) O (CR R) O (C alquilo)-C (O) (CR R) O (CR R) NR R-C (O) CRˣRˣS (O) ₂ (C₁₋₃ alkyl),-C (O) CR R NR S (O) (C alquilo)-C (O) CRˣRˣOC (O) (C₁₋₃ alkyl),-C (O) (CR R) NR R-C (O) (CR R) NR (C cianoalquilo)-C (O) (CR R) NR (C hidroxialquilo)-C (O) (CRˣRˣ) ₀₋₂NRˣ (C₁₋₃ fluoroalkyl),-C (O) (CR R) NR (C hidroxi-fluoroalquilo)-C (O) (CR R) NR (CH) O (C hidroxialquilo)-C (O) (CR R) NR (CH) NR C (O) (C alquilo)-C (O) (CR R) NR ((CR R) O (C alquilo))-C (O) (CRˣRˣ) ₀₋₂N ((CRˣRˣ) ₁₋₂O (C₁₋₂ alkyl)) ₂,-C (O) (CR R) NR (CR R) NR R-C (O) CR (NH) (CR R) NR R-C (O) CR (NH) (CR R) NR C (O) NR R-C (O) (CRˣRˣ) ₀₋₃NRˣ (CH₂) ₀₋₁C₍O₎₍C₁₋₃ alkyl),-C (O) (CRˣRˣ) ₀₋₃N ((C
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- 中国工程科技知识中心
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- http://www.ckcest.cn/home/
