The invention provides compositions for preventing chronic feline kidney disease, e.g., chronic renal failure comprising from about 33 to about 38%, or from about 28 to about 35% protein and compositions for treating chronic kidney disease in felines comprising from about 26 to about 30%, or from about 28 to about 30%, wherein the protein comprises at least about 75% vegetable protein and methods for using such compositions to prevent or treat chronic feline kidney disease. The invention also provides methods for preparing the compositions, articles of manufacture comprising the compositions, and means for communicating information about the compositions, methods, and articles of manufacture.