NORMAN N KIM,WILLIAM K MCVICAR,THOMAS G MCCAULEY,PRAKASH JAGTAP
申请号：
IN9039/DELNP/2012
公开号：
IN2012DN09039A
申请日:
2012.10.18
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Provided herein is a method of reducing intraocular pressure (IOP) in humans using N6-cyclopentyladenosine (CPA), CPA derivatives or prodrugs or enhanced cornea permeability formulations of CPA. In one embodiment, the invention is directed to CPA derivatives or prodrugs that are permeable to the cornea. In another embodiment, the invention is directed to uses of certain compounds in human subjects for reducing andlor controlling elevated or abnormally fluctuating IOPs in the treatment of glaucoma or ocular hypertension (OHT).
