PIER LUCIO ANELLI,LUCIANO LATTUADA,ROBERTA FRETTA,AURELIA FERRIGATO,PIER FRANCESCO MOROSINI,SILVIA CERAGIOLI,FULVIO UGGERI
申请号:
PT10781898
公开号:
PT2503990E
申请日:
2010.11.23
申请国别(地区):
PT
年份:
2013
代理人:
摘要:
The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions.