The present Invention relates to the use of a composition based on bacteria and / or yeasts and / or other Microorganisms, taken Singularly or in combination,For the treatment of the symptoms of and / or for treating irritable bowel syndrome (IBS) or also similar pathologies affecting the gastrointestinal Apparatus.In particular, the bacteria are selected from the following genera: Lactobacillus, Bifidobacterium, Bacillus, Streptococcus, Propionibacterium, aerococcus and Lactococcus, Enterococcus.The present invention relates to the use of a composition based on bacteria and/or yeasts and/or other microorganisms, taken singularly or in combination, for the treatment of the symptoms of and/or for treating Irritable Bowel Syndrome (IBS) or also similar pathologies affecting the gastrointestinal apparatus. In particular, the bacteria are selected from the following genera: Lactobacillus, Bifidobacterium, Bacillus, Propionibacterium, Streptococcus, Lactococcus, Aerococcus and Enterococcus.