SEO, Sung Wook,서성욱,PARK, Han Soo,박한수,SHIN, Seung Han,신승한,LEE, Hye Won,이혜원
申请号:
KRKR2013/009453
公开号:
WO2014/088205A1
申请日:
2013.10.23
申请国别(地区):
WO
年份:
2014
代理人:
摘要:
The present invention relates to a cartilage scaffold prepared using benign cartilaginous tumor cells, and a preparation method therefor, and specifically, to: a method for preparing a cartilage scaffold by culturing benign cartilaginous tumor cells, isolating tumor cells and extracting a cartilage scaffold a cartilage scaffold prepared by the method and a composition, an injectable medicine and a graft for cartilage regeneration, containing the cartilage scaffold as an active ingredient. The cartilage scaffold of the present invention prepared from benign cartilaginous tumor cells, or cartilage cells prepared by adding the cartilage scaffold to a cartilage differentiation medium and culturing the same, would be effectively used for regenerating a damaged cartilage by being variously formulated in the form of an injectable medicine, a graft or the like. The cartilage scaffold of the present invention is a human type cartilage scaffold prepared using benign cartilaginous tumor cells collected from human patients, and thus it is possible to provide a clinically applicable composition for cartilage regeneration by removing dangers such as transplant rejection, an infection from a zoonotic source, and the like which can be involved when an animal cartilage scaffold used in a conventional study is used.La présente invention concerne un échafaudage de cartilage préparé au moyen de cellules de tumeur cartilagineuse bénigne, et un procédé de préparation de celui-ci, et spécifiquement : un procédé de préparation dun échafaudage de cartilage par culture de cellules de tumeur cartilagineuse bénigne, disoler des cellules tumorales et lextraction dun échafaudage de cartilage un échafaudage de cartilage préparé par le procédé et une composition, un médicament injectable et un greffon pour la régénération du cartilage, contenant léchafaudage de cartilage en tant que substance active. Léchafaudage du cartilage de la présente invention préparé à partir de cellules de tumeur cartil