Pouzití uromodulinu pro prípravu sérového markeru pro in-vitro stanovení nefropatie, pricemz snízení hodnoty uromodulinu indikuje nefropatii.In the present invention, there is disclosed the use of uromodulin for the preparation of a serum marker for in-vitro determination of nephropathy, whereby the reduction of the uromodulin amount indicates the nephropathy.