PROBLEM TO BE SOLVED: To provide a therapeutic agent for preventing and ameliorating osteoporosis or food and drink such as health food in which a tissue or type from which collagen is derived are identified and used.SOLUTION: This invention provides a therapeutic agent for preventing and ameliorating osteoporosis or food and drink such as health food, being a collagen mixture containing type I collagen as a main component, and comprising collagen derived from bone (biological component containing the same) and/or type I collagen and type III collagen (biological component containing them).【課題】コラーゲンの由来組織や型を特定して用いた骨粗鬆症予防及び改善治療剤又は健康食品等の飲食物の提供。【解決手段】タイプＩコラーゲンを主成分とするコラーゲン混合物で、骨由来コラーゲン（これを含む生体成分）及び又はタイプＩコラーゲン及びタイプＩＩＩコラーゲン（これらを含む生体成分）より成る骨粗鬆症予防及び改善治療剤又は健康食品等の飲食物。【選択図】なし
