The present invention relates to an antiviral composition including boric acid, citric acid, and zinc. Especially, the composition has an activity of inhibiting protein expression of Papilom virus. Provided is a novel antiviral agent has an activity stronger than that of an existing antiviral agent. The antiviral composition according to the present invention can include 0.001-10 wt% of boric acid, 0.001-10 wt% of citric acid, and 0.001-10 wt% of zinc.본 발명은 활성성분으로 붕산, 구연산, 아연을 포함하는 항바이러스제 조성물에 관한 것이다. 특히, 파필로마 바이러스의 단백질 발현을 억제시키는 활성을 가지고 있다.