A cannula-needle with a protective member includes a needle holder that holds a needle, which is designed to be coaxially coupled with a cannula for making an injection into a blood vessel, and which has a stem having a longitudinal axis, a distal tip and a transverse engagement member in the proximity of the tip； a cannula holder, with the cannula extending from a distal end thereof, and with an inner cavity mating with the needle holder and having inner walls formed at the opposite proximal end； a protective member protecting the needle tip and movable from a disabled position to an enabled position, in which it is irreversibly placed beyond the needle tip after use of the cannula-needle, the protective member being housed between the inner walls of the inner cavity in the disabled position.
