FORME MEDICAMENTEUSE SOLIDE DU CHLORHYDRATE DE N-(2,6-BIS(1-METHYLETHYL)PHENYL)-N'-((1-(4-(DIMETHYLAMINO) PHENYL)CYCLOPENTYL)METHYL)UREE ET COMPOSITIONS, PROCEDES ET KITS S'Y RAPPORTANT

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专利权人:

MILLENDO THERAPEUTICS; INC.

发明人:

MATUNAS, ROBERT,CHEN, HERMAN,BETANCOURT, AIMESTHER,UZARAMA, CHARLES,THIBERT, ROCH

申请号：

CA2962597

公开号：

CA2962597A1

申请日:

2015.09.25

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

A novel solid drug form of N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea hydrochloride (also referred to "ATR-101") suitable for oral dosing, and to compositions, methods and kits relating thereto. ATR-101 has particular utility in the treatment of, for example, aberrant adrenocortical cellular activity, including adrenocortical carcinoma (ACC), congenital adrenal hyperplasia (CAH) and Cushing's syndrome.

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