WILLAM, ANITA,LEMMENS-GRUBER, ROSA,TZOTZOS, SUSAN JANE,FISCHER, BERNHARD,SHABBIR, WAHEED,LUCAS, RUDOLF
申请号:
CA2998443
公开号:
CA2998443A1
申请日:
2016.09.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A cyclic polypeptide comprising at least six contiguous amino acids from the amino acid sequence SEQ ID NO:1 Gly-Gln-Arg-Glu-Thr-Pro-Glu-Gly-Ala-Glu-Ala-Lys-Pro-Trp-Tyr for the treatment of autosomal recessive pseudohypoaldosteronism type 1 (PHA type 1B) or for the restoration of the Na+ transport capacity of mutated loss-of-function ENaC.