BURGOS MUNOZ, JAVIER SANTOS,RAMOS MARTIN, MARIA DEL CARMEN,SIERRA AVILA, SALETA,ALFARO SANCHEZ, JUAN MARIA,VELASCO ALVAREZ, JAVIER,RUMBERO SANCHEZ, ANGEL,RAMIREZ MORENO, CARLOS
申请号：
EP10748372
公开号：
EP2404599A4
申请日:
2010.03.05
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The invention describes the use of (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl-1-naphthalenyl propanoate derivatives, optionally mono- or di-methylated at the carbon in the alpha position of propanoic acid, of formula (I), where R is CH3CH2CO-, (CH3)2CHCO- or (CH3)3CCO-, its hydroxy acid forms and the pharmaceutically acceptable salts of said hydroxy acids, as neuroprotective compounds potentially useful for the prevention and/or treatment of neurodegenerative diseases, or of diseases associated with an unwanted oxidation or of age-associated pathological processes, or of epilepsy, epileptic seizures or convulsions.
