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REDOX DRUG DERIVATIVES
- 专利权人:
- 레드엑스 파마 리미티드;REDX PHARMA LIMITED
- 发明人:
- LINDSAY DEREK,린제이, 데렉,JACKSON PETER,잭슨, 피터
- 申请号：
- KR1020117029829
- 公开号：
- KR1020120025519A
- 申请日:
- 2010.05.17
- 申请国别(地区):
- KR
- 年份:
- 2012
- 代理人:
- 摘要：
- The present invention provides redox drug derivatives. In particular, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester, (3S)-3-(aminomethyl)-5-methylhexanoic acid, (3S)-1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-&alpha；-&alpha；-diphenyl-3-pyrrolidineacetamide, (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethyl-butyl]-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid and (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid redox derivatives.본 발명은 산화환원 약물 유도체를 제공한다. 특히, 9-플루오로-2,3-디히드로-3-메틸-10-(4-메틸-1-피페라지닐)-7-옥소-7H-피리도[1,2,3-데]-1,4-벤족사진-6-카르복실산, 1-에틸-6-플루오로-1,4-디히드로-7-(4-메틸-1-피페라지닐)-4-옥소-3-퀴놀린카르복실산, (3R, 4R, 5S)-4-(아세틸아미노)-5-아미노-3-(1-에틸프로폭시)-1-시클로헥센-1-카르복실산 에틸 에스테르, (3S)-3-(아미노메틸)-5-메틸헥산, (3S)-1-[2-(2,3-디히드로-5-벤조퓨라닐)에틸]-α-α-디페닐-3-피로리딘아세트아미드, (1S,2S,3S,4R)-3-[(1S)-1-아세트아미도-2-에틸-부틸]-4-(디아미노메틸리덴아미노)-2-히드록시-시클로펜탄-1-카르복실산 및 (2R,3R,4S)-4-[(디아미노메틸리덴)아미노]-3-아세트아미도-2-[(1R,2R)-1,2,3-트리히드록시프로필]-3,4-디히드로-2H-피란-6-카르복실산 산화환원 유도체를 제공한다.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
