The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
Amy Hauck Newman,Mu-Fa Zou,Jonathan L. Katz
申请号:
US13739724
公开号:
US20130202529A1
申请日:
2013.01.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are benztropine analogs having the formula (I)in which Ar is a C6-C20 monocyclic aryl group or a C10-C20 bicyclic aryl group or a heteroaryl, heterocyclic, or arylheterocyclic group having 2 to 12 carbon atoms and one or more heteroatoms selected from the group consisting of N, O, S, P, and any combination thereof m=1 to 5 n=1 to 3 and R1 to R4 are as described in the specification or a pharmaceutically acceptable salt or solvate thereof pharmaceutical compositions and use thereof, e.g., in treating mental disorders.