VACCINATION PAR DE MULTIPLES CLADES DU VIRUS DE LA GRIPPE A H5

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专利权人:

NOVARTIS AG

发明人:

PODDA, AUDINO,RAPPUOLI, RINO

申请号：

CA2706619

公开号：

CA2706619C

申请日:

2008.11.25

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

H5N1 influenza viruses isolated fromanimals and humans since 2003 separate into distinctclades based on hemagglutinin amino acid sequences.According to the invention, multiple clades are usedin influenza immunization. Thus there is a prime-boostimmunization schedule where a subject receives apriming dose of a first clade of H5 influenza A virusand a boosting dose of a second clade of H5 influenzaA virus. There is also an immunogenic compositioncomprising hemagglutinin antigens from more thanone clade of H5 influenza A virus.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/