To provide agents for preventing or mitigating hearing loss which contains as an active ingredient a low molecular weight compound that can be produced relatively simply and inexpensively.SOLUTION: An agent for preventing or mitigating hearing loss contains one or more compounds selected from the group consisting of compounds represented by general formula (I) and, when Ris OH, of pharmaceutically acceptable salts of them.SELECTED DRAWING: None【課題】比較的簡便かつ安価に製造することができる低分子化合物を有効成分とする、難聴の予防又は改善剤の提供。【解決手段】一般式（Ｉ０）で表される化合物、並びに、Ｒ３がＯＨのときそれらの医薬的に許容される塩からなる群から選択される１種又は２種以上の化合物。【選択図】なし
