Disclosed is an amphiphilic copolymer that can be used in film-forming compositions for dermal applications. The amphiphilic copolymer is characterized by having a defined structure with a hydrophilic polymer backbone and pendant hydrophobic groups. When applied to the skin, the copolymer rearranges in contact with the lipid-rich domains of the outermost layer of the skin, resulting in stable film formation. The amphiphilic copolymer contains active ingredients covalently attached, such as sunscreens, humectants or colourings, resulting in skin immobilization of the active ingredient. The amphiphilic copolymer can also contain other active agents, such as fragrances, cosmeceuticals or dermatologically active drugs, covalently attached via a chemical bond that can be degraded under the physiological conditions found on the skin, resulting in sustained release of the immobilized active ingredient.