It refers to the positive Western Sahara modulation compound (PAMs) of acetylcholine α 7 (I) nicotine receptor, wherein R1, R2, R3, R4 and R5 are independently selected from H tar 1-c6, cyanogen, halogen, etc.； R6 is C1-C6, alquenilo C2-C6, alcox C1-C6, etc.； A7 is c-r7, N； A8 is c-r8, N and A9, respectively. This is c-r9, N； R7, R8, R9, R10 and R11 are selected from C, h, C1-C6, alquenilo C2-C6 and other substances, respectively. The most popular are [(s) - 1 - (6-isopropyl-pyridine-3-il) - ethyl] - acid amide (1s, 2S) - 2-phenyl-cycloacrylonitrile, [(s) - 1 - (5-methyl-pyridin-2-il) - ethyl] - acid amide (1s, 2S) - 2-phenyl-cyclopropane,There are others He also mentioned a pharmacological synthesis that is useful in the treatment of schizophrenia, cognitive disorders and so on.SE REFIERE A COMPUESTOS MODULADORES ALOSTERICOS POSITIVOS (PAMS) DEL RECEPTOR NICOTINICO DE ACETILCOLINA ALFA 7 DE FORMULA (I) DONDE R1, R2, R3, R4 Y R5 SE SELECCIONAN INDEPENDIENTEMENTE ENTRE SI, ENTRE H, ALQUILOC1-C6, CIANO, HALOGENO, ENTRE OTROS； R6 ES ALQUILO C1-C6, ALQUENILO C2-C6, ALCOXI C1-C6, ENTRE OTROS； A7 ES C-R7, N； A8 ES C-R8, N Y A9 ES C-R9, N； R7, R8, R9, R10 Y R11 SE SELECCIONAN INDEPENDIENTEMENTE ENTRE SI, H, ALQUILO C1-C6, ALQUENILO C2-C6, ENTRE OTROS. SON SOMPUESTOS PREFERIDOS [(S)-1-(6-ISOPROPOXI-PIRIDIN-3-IL)-ETIL]-AMIDA DEL ACIDO (1S, 2S)-2-FENIL-CICLOPROPANCARBOXILICO, [(S)-1-(5-METIL-PIRIDIN-2-IL)-ETIL]-AMIDA DE ACIDO (1S, 2S)-2-FENIL-CICLOPROPANCARBOXILICO, ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE ES UTIL EN EL TRATAMIENTO DE ESQUIZOFRENIA, TRASTORNOS COGNITIVOS, ENTRE OTROS.
