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Tricyclic tin compounds substituted by FGF receptor inhibitors
专利权人:
INCYTE CORPORATION
发明人:
WU, LIANGXING,ZHANG, COLIN,HE, CHUNHONG,SUN, YAPING,LU, LIANG,QIAN, DING-QUAN,XU, MEIZHONG,ZHUO, JINCONG,YAO, WENQING
申请号:
PE2014002433
公开号:
PE20150684A1
申请日:
2013.06.12
申请国别(地区):
PE
年份:
2015
代理人:
摘要:
The invention relates to a tricyclic tin compound in the formula, wherein W is NH; a is pyridan; R1 is h; R2 and R3 are h, CN, etc.; R4, R5, R6, R7, R8 are h, halo, C1-C6 asphalt, etc. It also refers to the pharmacological components of these substances, which inhibit one or more enzymes of the future generations fund and are useful in the treatment of diseases related to the future generations fund, such as cancer.La invencion se refiere a compuestos triciclicos de la formula I, donde W es NH; A es imidazol; R1 es H; R2 y R3 son cada uno H, CN, entre otros; R4, R5, R6, R7, R8 son cada uno H, halo, alquilo C1-C6, entre otros. Tambien se refiere a composiciones farmaceuticas de los mismos, que son inhibidores de una o mas enzimas del FGFR y son utiles en el tratamiento de enfermedades asociadas con el FGFR tales como cancer
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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