A system for the heat treatment of industrial quantities of food or pharmaceutical articles. The system includes an oblong enclosure that is sealed and can be pressurized and having a median longitudinal axis and an inlet for the injection of a heat transfer fluid, an inlet door for the insertion of articles, a support for the articles, which support can be arranged along the median longitudinal axis, such that the articles are placed inside a central space in the enclosure, a defined lateral space being provided between the enclosure and the central space. The enclosure includes an agitation means for agitating the heat transfer fluid, which means is arranged laterally in relation to the central space, in the lateral space located between the enclosure and the central space, to allow the circulation of the heat transfer fluid in a longitudinal direction parallel to the median longitudinal axis.