In the present invention, a biodegradable scaffold bone graft embedded in collagen is disclosed, which includes: a scaffold made of biodegradable material； and a collagen embedding matrix portion which completely encompasses the scaffold. The above-mentioned scaffold bone graft can increase the micro-porosity of the scaffold to enable cells to grow adhesively thereon. Compared with the scaffold only, the above-mentioned scaffold bone graft has high hydrophilicity. Hence, the scaffold bone graft can efficiently absorb tissue fluid and blood, and have increasing contact area with soft or hard tissue to achieve osteoconduction. Furthermore, the collagen embedding matrix portion can also serve as a carrier to encompass other bone graft materials and drug molecules. The present invention also relates to a method for manufacturing the above-mentioned scaffold bone graft.本發明係有關於一種骨科用生物可分解性補綴物，包括：一支架，該支架之材料係為生物可分解性材料；以及一膠原蛋白包埋層，該膠原蛋白包埋層係完全包埋該支架。上述補綴物能增加支架之微孔性，讓細胞輕易貼附表面進行生長，且能增加支架之親水性，有效吸附組織液及血液，並增加與軟組織或硬組織接觸表面積，而可達到誘導骨生成的功能，膠原蛋白包埋層亦可作為包埋其他骨填料及藥物之載體。本發明亦關於一種上述骨科用生物可分解性補綴物之製造方法。
