MACDONALD, Lynn L,MURPHY, Andrew, J. AJ,TU, Naxin N,VORONINA, Vera V,GURER, Cagan C,‧麥克唐納,‧莫菲,‧圖,‧沃羅寧那,‧古雷爾
申请号:
HK16101695.8
公开号:
HK1213908A
申请日:
2016.02.17
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The invention provides genetically modified non-human animals that express chimeric human/non-human T cell co-receptor polypeptides (e.g. CD4, CD8α, CD8β), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.