THE JOHNS HOPKINS UNIVERSITY;FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.;The United States of America, as represented by the Secretary, Department of Health and Human Servic
发明人:
HENGLI TANG,EMILY M. LEE,ANIL MATHEW THARAPPEL,HONGJUN SONG,GUO-LI MING,WEI ZHENG,MIAO XU,SHU YANG,RUILI HUANG,WENWEI HUANG,KHALIDA SHAMIM,HAO LI
申请号：
US16718343
公开号：
US20200121672A1
申请日:
2019.12.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention concerns the use of emetine compounds for the treatment or prevention of Flavivirus infections, such as dengue virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus infection, by administering an emetine compound such as emetine or cephaeline, or a combination of two or more emetine compounds, to a subject in need thereof； methods for inhibiting Flavivirus infections such as dengue virus infections in a cell in vitro or in vivo； pharmaceutical compositions； packaged dosage formulations； and kits for treating or preventing Flavivirus infections, such dengue virus infections.
