Vitamin D based preparations are disclosed comprising a complex of de-glycosylated vitamin D-binding protein (also called GcMAF), vitamin D3 or its analogues, and at least on unsaturated fatty acid. The preparations may include an aqueous alcoholic saline solvent, and the unsaturated fatty acid can be oleic acid or eicosapentaenoic acid. Orally administrable compositions comprising the aforementioned preparations encapsulated in liposomes are also disclosed, along with methods for the production of the aforementioned preparations.