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AGENT BIOCOMPATIBLE DE DISPERSION DE NANOPARTICULES EN MILIEU AQUEUX À L'AIDE DE POLYMÈRE MIMÉTIQUE DE PROTÉINE ADHÉSIVE DE MOULE
专利权人:
HANWHA CHEMICAL CORPORATION
发明人:
HYEON, TAEGHWAN,NA, KUN,LING, DAISHUN,PARK, WOORAM
申请号:
EP11852486
公开号:
EP2658896A4
申请日:
2011.12.28
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Provided are a mussel adhesive protein-mimetic dispersion stabilizing agent to disperse nanoparticles in an aqueous medium, a colloidal solution including nanoparticles dispersed and stabilized by the dispersion stabilizing agent, and a contrast agent including the colloidal solution. More particularly, the mussel adhesive protein-mimetic dispersion stabilizer is a polyethyleneimine-graft-(poly-ethyleneglycol;polyDOPA) PEI-graft-(PEG;PDOPA). The graft polymer is formed of two parts. One is polyethyleneglycol grafted with a polyethyleneime which has an affinity to an aqueous medium, and the other is polyDOPA which has an affinity to the surface of nanoparticles. Because of those characteristics, the stabilizer shows a stable dispersion of nano particles in the aqueous medium.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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