James F. Martin,Yuka Morikawa,Todd Ryan Heallen,John Leach
申请号：
US16544209
公开号：
US20200002702A1
申请日:
2019.08.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
