Methods for modulating cyclic nucleotide-mediated signaling in cardiac myocytes and compositions

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专利权人:

Matthew Movsesian;Manuela Zaccolo

发明人:

Matthew Movsesian,Manuela Zaccolo

申请号：

US14800657

公开号：

US09994830B2

申请日:

2015.07.15

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention provides a polypeptide possessing anti-hypertrophic activity in a cardiac myocyte, wherein the polypeptide is a mutant variant derived from wild-type PDE3A1 protein and wherein the wild-type PDE3A1 protein has the amino acid sequence given in SEQ ID NO:1 at amino acid position 146 to 1141.

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中国工程科技知识中心

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http://www.ckcest.cn/home/