With the method for what large-scale production 1- [(2- bromophenyls) sulfonyl] -5- methoxyl groups -3- [(4- methyl-1s-piperazinyl) methyl] -1H- indoles dimethanesulfonate monohydrates农业专利-农业学术服务平台

发明人:: NIROGI, Ramakrishna,罗摩克里希纳．尼罗吉,羅摩克里希納．尼羅吉,KAMBHAMPATI, Rama Sastri,拉马．萨斯特里．卡姆巴姆帕蒂,拉馬．薩斯特里．卡姆巴姆帕蒂,SHINDE, Anil Karbhari,阿尼尔．卡巴里．欣德,阿尼爾．卡巴里．欣德,JASTI, Venkateswarlu,文卡特斯瓦卢．贾斯蒂,文卡特斯瓦盧．賈斯蒂,罗摩克里希纳.尼罗吉,羅摩克里希納.尼羅吉,拉马.萨斯特里.卡姆巴姆帕蒂,拉馬.薩斯特里.卡姆巴姆帕蒂,阿尼尔.卡巴里.欣德,阿尼爾.卡巴里.欣德,文卡特斯瓦卢.贾斯蒂,文卡特斯瓦盧.賈斯蒂

摘要：: The method for being suitable for large scale preparation 1- [(2- bromophenyls) sulfonyl] -5- methoxyl groups -3- [(4- methyl-1s-piperazinyl) methyl] -1H- indoles dimethanesulfonate monohydrates； the compound is selective 5-HT6 receptor antagonists, it is intended to what Alzheimer disease and the symptomatic treatment of other memories and cognitive disorder (such as attention deficit hyperactivity disorder, Parkinson's disease and schizophrenia).適用於大規模製備1‑[(2‑溴苯基)磺酰基]‑5‑甲氧基‑3‑[(4‑甲基‑1‑哌嗪基)甲基]‑1H‑吲哚二甲磺酸鹽一水合物的方法，該化合物是選擇性5‑HT6受體拮抗劑，旨在用於阿爾茨海默病以及其他記憶和認知障礙（例如注意缺陷多動障礙、帕金森病和精神分裂症）的對症治療。