The University of Greenwich;Curadev Pharma Pvt Ltd
发明人:
Tammy Savage,Stephen Wicks,John Mitchell
申请号:
US14333417
公开号:
US20150025023A1
申请日:
2014.07.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides a method for preparing sulphoalkyl ether-β-cyclodextrin. The method comprises first contacting cyclodextrin with a base to form activated cyclodextrin. The method then comprises separately contacting the activated cyclodextrin with an alkyl sultone to form sulphoalkyl ether-β-cyclodextrin. The activation reaction is carried in batch and the sulphoalkylation reaction is carried out under continuous flow conditions.