(57)< Abstract > The to control discharge formulation containing the Glico pyro rate which is converted being the composition which becomes, when prescribing that, medicine reason action of the said Glico pyro rate exceeding 12 hours, the medicine composition which it reveals.制御放出製剤化したグリコピロレートを含有してなる組成物であって、それを投与したときに該グリコピロレートの薬理作用が12時間を超えて発現する医薬組成物。