Chevalier, Brett,Marson, Alexander,Young, Richard A.,Foreman, Ruth,Jaenisch, Rudolf
申请号：
AU2014224119
公开号：
AU2014224119B2
申请日:
2014.09.12
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
#$%^&*AU2014224119B220170803.pdf#####EDITORIAL NOTE 2014224119 - There is 1 page of Abstract - The Abstract is the 93d page of the SpecificationABSTRACT The invention provides compositions and methods of use in reprogramming somatic cells. Compositions and methods of the invention are of use, e.g., for generating or modulating (e.g., enhancing) generation of induced pluripotent stem cells by reprogramming somatic cells. The reprogrammed somatic cells are useful for a number of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a pluripotent state and/or enhances the speed and/or efficiency of reprogramming. Certain compositions and methods relate to modulating the Wnt pathway.
