INSTYTUT IMMUNOLOGII I TERAPII DOSWIADCZALNEJ POLSKIEJ AKADEMII NAUK
发明人:
ZUZIAK EWA,GAMIAN ANDRZEJ,GORSKI ANDRZEJ,LIPINSKI TOMASZ,GÓRSKI ANDRZEJ,LIPI&NacuteSKI TOMASZ
申请号：
PL38638108
公开号：
PL213166B1
申请日:
2008.10.29
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
The subject the present invention is a method of producing a pharmacologically stable form of purified and lyophilised bacteriophage preparations of increased stability and antibacterial activity, characterized in that phages produced from a bacterial lysate, for example by ultrafiltration on ultrafiltration membranes, containing a high molecular weight preparation of purified phages is stabilised most preferably with a probiotic extract in the presence or absence of neutral salts and/or organic solvents, lyophilised, characterised via HPLC chromatography, by SDS-PAGE, and bacterial lysis biological assays, and then stored under a vacuum, where the active lyophilisate is destined for phage therapy of infections and tumors.
