ANDREA GAMBINI,WALTER CABRI,DANIELE CICERI,LUCA DOMENIGHINI,FEDERICO PETERLONGO
申请号:
PT14789196
公开号:
PT3060556T
申请日:
2014.10.09
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
The present invention relates to a new anhydrous crystalline form of Cabazitaxel of formula (I), designated as form H. A further object of the present invention is a processes for the preparation of the above mentioned form H by recrystallization of Cabazitaxel from a mixture of decanoyl- and octanoyl triglycerides or from glycerol trioctanoate. Form H of Cabazitaxel is useful for the preparation of Cabazitaxel, Cabazitaxel salts, and polymorphic forms thereof. It is also particularly useful as a medicament, especially for the treatment of cancers.