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PHENYLEPHRINE LIQUID FORMULATIONS COMPRISING POLYETHYLENE GLYCOL WITH LOW ALDEHYDE CONTENT
专利权人:
WYETH
发明人:
BUBNIS, WILLIAM,SHIELD, STEPHANIE,HOSKOVEC, GAYLE, P
申请号:
NZ57414807
公开号:
NZ574148A
申请日:
2007.07.11
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is an oral liquid pharmaceutical composition comprising: (a) phenylephrine or a pharmaceutically acceptable salt thereof and (b) substantially aldehyde-free polyethylene glycol, wherein the substantially aldehyde-free polyethylene glycol has less than 10 ppm total aldehyde content and maintains said level of aldehyde content for at least one year (c) a second active agent selected from an analgesic, a decongestant, an expectorant, an anti-tussive, an antipyretic, an anti-inflammatory agent, a cough suppressant and an antihistamine and (d) a buffering agent which maintains a pH below 5.4 in the composition. Also disclosed is the use of the phenylephrine formulation for treating a cold, flu, or allergy in mammals.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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