Alan S. Cross;Wendell D. Zollinger;Steven M. Opal;Apurba K. Bhattacharjee
发明人:
Alan S. Cross,Apurba K. Bhattacharjee,Wendell D. Zollinger,Steven M. Opal
申请号：
US14636951
公开号：
US09616116B2
申请日:
2015.03.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides an immunogenic composition of a lipopolysaccharide vaccine and a non-alum adjuvant. The immunogenic composition may be detoxified J5 core lipopolysaccharide of Escherichia coli non-covalently complexed with group B meningococcal outermembrane protein. Also provided are methods for preventing an infection caused by a Gram-negative bacteria in an individual via administering the immunogenic compositions to the individual.
