ARZENO, HUMBERTO BARTOLOME,FILONOVA, LUBOV,GOLDSTEIN, DAVID MICHAEL,GONG, LEYI,LOE, BRADLEY E.,O'BRIEN, ERIN M.,PALMER, WYLIE SOLANG,ROTSTEIN, DAVID MARK,SILVA, TANIA,TAN, YUN-CHOU
申请号:
CA2799328
公开号:
CA2799328C
申请日:
2011.06.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compounds of formula I or pharmaceutically acceptable salts thereof, wherein R5 is a group of formula (a) or (b): and wherein m, n, p, q, X, Y, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity.