THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
CHENG, JIANJUN,TANG, LI
申请号:
EP11846037
公开号:
EP2646818A4
申请日:
2011.11.30
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention provide a silica nanoparticle comprising a non-porous matrix of silicon-oxygen bonds, wherein the matrix comprises organic agents conjugated to silicon or oxygen atoms in the matrix, the organic agents are conjugated to the matrix through linker L groups, wherein the linker L comprises, for example, an ester, urea, thiourea, or thio ether group, and wherein the diameter of the nanoparticle is about 15 nm to about 200 nm. The invention also provides novel methods of making and using the silica nanoparticles described herein.